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Denotes lack of sanity in large quantity.
You're as mad as a box of frogs.
by GjjG April 26, 2006
An extremely ugly individual
James - "Did you check out that girl at the bar?"

Michael- "Yeah! She was a right box of frogs!"
by Cuban_Cigar April 18, 2011
A term meaning temporary insanity in situation or conduct.

x - "omg noob asdf wickkle wickkle im pregnant and you're the mother!"
y - "you're madder than a box of frogs you are".

x- "omg i killed 18 guys in a row on 2142"

y- "yes, i saw that, it was madder than a box of frogs".
by crashmctavish November 16, 2006