Short for "best friends".

Betsies means best friends. It can be used on the net or in the real world.

Friends who have each other's backs, look out for each other, spend lots of time together, and are just really good friends.
They have inside jokes together, they go to the park and swing on swing sets, get ice cream, go to the beach, go to concerts, go bowling, and basically any activity that they like doing together as friends.

the coolest friends in the whole wide world

A slang term for best-friend...Goes hand in hand with bestest friend...
One who plays Yatzee with you...Drinks with you...Comes over just because your having a bad day...Or even blows off a date to hang out with you...Sometimes they watch "The Emperors New Grove" together...Have Fridays on Tuesdays night, and together graffiti a wall...

Term used to describe the coolest and best friends in the whole wide world; Besties tend to be badasses.

A word that means best friends. Is usually said by teenage girls who are insecure about themselves and therefore calls everyone they come in contact with a "besty." She will generally comment "besties," on every picture of herself with someone else tagged on facebook.

The word is pronounced "best-ees". It rhymes with testies.