It means "keep on doing what you do". i.e. "keep raping girls or killing dogs, or whatever".
Michael Vick: So, I got this big game coming up.

Kobe Bryant: Be epic.

Michael Vick: Yeah, we might win it. But if we don't, I'll just go home and drown a few puppies. Then I'll feel better. You be epic too, Kobe.

Kobe Bryant: I was epic last night when I slipped this girl a roofie and fucked her in the ass.

Michael Vick: High five!
by Michael Grant January 09, 2011

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