Top Definition
(noun) A drug cocktail consisting of Viagra and ecstasy. Almost always taken by males to prevent E dick. Associated with an increased risk of priapism.
Ann: Oh my! You're on V and E??
Sam: Yep. And it's killing me!
Ann: I think I might know how to help...
by Luciano Del Purgatorio June 21, 2006
6 Words related to V and E

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