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1.
UES
an acronym for the upper east side of Manhattan. The UES refers to 57th through 96th streets, east of 5th avenue. The avenues on the UES are: Madison, Park, Lexington, 3rd, 2nd, 1st, York, and East End.

The teenagers of the UES have a reputation for being very posh, stuck up, and wealthy. There are many infamous private schools on the UES, including Brearley, Chapin, Dalton, Spence, and Marymount. Brearley and Chapin have a huge rivalry. However, contrary to popular belief, the school called Constance-Billard, from the Gossip Girl series, was invented for the series, and does not exist in the real world.
girl 1: where do you go to school?

girl 2: I go to The Brearley School, on the UES.
by macubed58 November 22, 2009
 
2.
UES
UES is an abbreviation for Upper East Side. Used by New York City dwellers to describe that part of the city.
My friend John is dating some chic who lives on the UES.
by Streamwalker August 20, 2004