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1.
This happens when you make a twitter and say to yourself "im not even gonna use this" but then you end up tweeting about every single stupid thing in your life.
It is possible to have a Twitter with out catching the Twitter Syndrome.

But be warned, 4 out of 5 people have Twitter Syndrome.
(Twitter page)

john: i just woke up, hope its a good day!

john: headed off to school bleh ...

john: man i hate math class!

john: yes finally switching classes im going to see her<3

john: cant stop thinking about her<3

mike: GODDAMNIT JOHN NO ONE GIVES A FUCK ABOUT YOUR LIFE YOU DUMB CUNT! damn twitter syndrome >:(
by hailysComet April 11, 2010
 
2.
When someone sends you a message or IM and it's in a bunch of short abbreviated incomplete sentences that are less than 140 words.
Mike: We have more slides to watch. Waiting for PA room
Lunch won't be til late.

Me: HAHA dude you have Twitter Syndrome.
by rubygal September 23, 2009