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1.
Used on Twitter.com

-Term used for regretting a posted Tweet.
"I'm totally experiencing Tweegret after that last post."
by GSMproductions July 22, 2009
 
2.
the feeling that one gets that one might be missing out, by not participating in what seems to be a largely vacuous fad called Twitter.
I felt a twinge of tweegret, when I learned that Kim Jong Il now has a twitter account.
by caveatdumptruck August 21, 2010