While in modern usage, this is more often phrased as "take a chill pill", meaning "calm the fuck down", decades ago this was closer in meaning to "fuck off and die" as in "follow the lead of Hermann Göring and swallow a cyanide capsule".
Buddy, you need to take a pill.
by Uncle Red Dog March 7, 2017
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An expression of speech used in retort to someone who is behaving like a lunatic. Implies that the individual depends on medicine to function, and that his/her erratic behavior can be attributed to missing a dose of said medicine.
Person 1: 'Good morning'

Person 2: 'WHATS SO FUCKING GOOD ABOUT IT ASSHOLE?!!!'

Person 1: 'Take your pills man, holy shit'
by k_man_96 January 13, 2019
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Rather stay in a fake world than the hard reality one. Taken from the movie Matrix. Blue pill fake world, red pill reality.
I'm gonna take the blue pill and not deal with it.
by Ulysses4001 November 5, 2013
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Originating from the movie The Matrix, this colloquial term means to face the hard reality instead of staying inside the comfort zone of fantasy. Synonym of "face it". Antonym of "take the blue pill".
After procrastinating for 5 hours on the Internet, I decided to take the red pill and start the long essay assignment.
by cutesy pastel living doll March 7, 2014
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Something that you say to someone when they need to calm down. if someone is stressed .
if someone is nagging you, you say , "God , Take A Chill Pill!"
by Hana jj August 8, 2006
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From the first Matrix movie. Taking the red pill opens the soon-to-be Neo's eyes to the fantasy that he had been living in. Morpheus says to Neo "You have to understand that many people are not ready to be unplugged, and many of them are so inured, so hopelessly dependent on the system that they will fight to protect it."

Contrast with taking the blue pill. If Neo would have taken the blue pill, he would have stayed within the Matrix and been blind to reality.
Morpheus asks pre-Neo Keanu to take the red pill. As Neo reaches for the red pill Morpheus warns Neo "Remember, all I'm offering is the truth. Nothing more."

by Peakey April 6, 2006
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