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1.
Something that you say to someone when they need to calm down. if someone is stressed .
if someone is nagging you, you say , "God , Take A Chill Pill!"
by Hana jj August 08, 2006
 
2.
To do hydrocodone.
I would've been bored as hell the airplane trip, but fortunately my friend told me to take a chill pill so I slept through it.
by smokeyythebear August 19, 2008