Top Definition
Classic N64 fighting game, updated to game cube. All of the nintendo characters convene in the game to beat the snot out of each other with special moves and various weapons and tools. Gameplay is beautifully simple yet strategic, and even retards like me who can't play video games can develop some game if they play it enough. Best in 4 player mode.
They smashed (Played Smash Brothers) until their eyes bled.
by Ben J. August 29, 2006
1 more definition
Brothers that are known to sleep with lots of girls and "smash" that thing in the bedroom. A.K.A. Brothers that handle business in the bedroom to the point were she says she loves you and you just met the female.
"I put the smash brothers on her and shes been hooked ever since."
by tylii fliy October 17, 2008

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