Like saying "yo mama" but instead you say "ya sista" can be used for anything. More as an insult. Does not matter whether or not the person has a sister.
Guy 1:"Yo you looked like crap the other night at the party."
Guy 2:Ya sista looked like crap that sloppy hoe!"
by Icesakamami November 9, 2007
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A Hipster or Scenester with pants so tight it is as if they melted their legs and actually poured themselves into these pants, sometimes with bellbottoms sometimes not.

These men look as if the are wearing their 'younga 'sistas pants. visually unappealing, Tight and overall just plain Unacceptable!
HEY MARK ! check out those sista pants comin down the way....BOOYAH
by Rock n Roll Justice Council October 19, 2010
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Awesomely handsome brothers-in-law who are married to equally beautiful sisters.
Tan Keith is the best Sista-brotha this side of the James River. Our wives, whom are sisters, are so lucky to be married to us.
by DJ Tan-NERD September 19, 2020
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Relating to the restaurant chain Chipotle, your Shipole Sista is your close friend. You are her Shipole Sista and she yours. You have inside jokes are goofy and crazy around each other. You can always rely on your Shipole Sista for a good laugh.
Girl one "who are they?"

Girl two "that's (insert name) and (insert name), they are Shipole Sistas."
by hey_there_delilah January 29, 2022
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a person that is very close to you and you love like a sister. you tell them everything and are best friends. you are almost always with each other. sista frans are BEYOND just friends
Shea: is that girl Katie your friend?
Carly: She's not only my friend, she's my sista fran

or
Katie: hey sista fran, what's up?
Carly: nothing much, wanna hang out. go shopping or something?
by runnergirl365 February 6, 2011
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closer than a friend, not as annoying as a sister.
oh shes just my sista-frien' we keep it fo' real. my sista from another mister.
by Alex & Danielle June 13, 2008
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