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1.
Brilliant and nerdy alternative to the word 'sexy' first thought to be typoed by someone on MSN messenger.

It's supposed to be a cooler version, due to how it sounds.
Damn that girl is so sexu!
by Crabby January 05, 2005
 
2.
A luxury sedan for men only.
I'm going to take the guys to the game (but not their wives) in the Sexus.
by martyv March 06, 2007
 
3.
A sexual nexus, aka sexual connection.
He felt that he had a real sexus with the hottie at the bar.
by Amber HP November 22, 2007