Top Definition
Sem
Abbreviation of "awesem," a slang version of "awesome." used commonly on student film sets in the Chicago area to refer to something extremely cool or pleasing.
- "hey, the car mount is ready."
- "SEM."
#awesome #cool #great #perfect #badass #sick #sweet
by SylviaToo January 23, 2010
Sem
The greatest person in the history of the universe, everyone who meets him wants to be him or be with him.
Man I wish I was Sem!
#sem #awesem #great #awesome #sex
by Erin Maxwell May 27, 2011
SEM
Sexually Enhanced Males
"Did you see that guy over there?"
"OMG yesssss, must have been a SEM"
#sexually #enhanced #male #males #men
by urbandictionaryperson123456789 October 23, 2011
SEM
SEM: Self-centered Egoistic Maniac

A person who has the highest opinion for himself/herself that is very annoying.

Someone who is obsessed with himself.
Person #1: Look at her. She is obsessed with herself.
Person #2: She is such a SEM.
#self-centered #egoistic #maniac #narcissist #annoying
by Jana-Blonde June 29, 2009
SeM
Sem: Semen Eating Monster
A ugly, fat, skanky, female. Most likely has some sort STD, like crabs or scabies. Likes to fuck anything with a penis. An outcast.
a) That bitch is such a SeM, its discusting.
b) Fuck that SeM and her skanky ass.
#fat #ugly #hairy #gross #std factory
by kjdfhgfhdf March 07, 2007
sem
(n) Ebonics for the number seven.
"I keep it crunk twenny fo'-sem!"
#seven #language #ebonics #number #fif
by Lil Dre March 21, 2006
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