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1.
Sem
Abbreviation of "awesem," a slang version of "awesome." used commonly on student film sets in the Chicago area to refer to something extremely cool or pleasing.
- "hey, the car mount is ready."
- "SEM."
by SylviaToo January 23, 2010
22 8
 
2.
SEM
Sexually Enhanced Males
"Did you see that guy over there?"
"OMG yesssss, must have been a SEM"
by urbandictionaryperson123456789 October 23, 2011
16 10
 
3.
Sem
The greatest person in the history of the universe, everyone who meets him wants to be him or be with him.
Man I wish I was Sem!
by Erin Maxwell May 27, 2011
22 16
 
4.
SEM
SEM: Self-centered Egoistic Maniac

A person who has the highest opinion for himself/herself that is very annoying.

Someone who is obsessed with himself.
Person #1: Look at her. She is obsessed with herself.
Person #2: She is such a SEM.
by Jana-Blonde June 29, 2009
19 27
 
5.
SeM
Sem: Semen Eating Monster
A ugly, fat, skanky, female. Most likely has some sort STD, like crabs or scabies. Likes to fuck anything with a penis. An outcast.
a) That bitch is such a SeM, its discusting.
b) Fuck that SeM and her skanky ass.
by kjdfhgfhdf March 07, 2007
30 43
 
6.
sem
(n) Ebonics for the number seven.
"I keep it crunk twenny fo'-sem!"
by Lil Dre March 21, 2006
11 33