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1.
One who acts as a sasquatch; a d-bag.
Get your ass over here ya sasq!

Rodriguez: AY WAY, Pancho couldn't get the pesos.
Umberto: Damn foo he's such a Sasq.
by Sasquatchio April 14, 2008
 
2.
Snappy Answers to Stupid Questions, a regular segment from Mad Magazine
Q: Did you catch that fish?
A: No, I talked him into giving himself up.
A: No, I was sitting here minding my own business when the crazy thing jumped into my pail.
A: No, it's a plastic model to get people like you to start fascinating conversations.

Can be used sarcastically:
"What's up?"
"The sky."
"Ooh, SASQ!"
by IAmTheByron June 26, 2009