An affliction that effects men everywhere. Symptoms are similar to PMS, but much more extreme. They include nagging like a bitch, complaining about irrelevant events, and inability to continue being a productive human being. They also include weeping and moaning and other forms of whining.
"Is Mike coming to the bar with us?"

"Nahh. He came down with a case of pussy syndrome and is staying home to watch Glee."
by SuperfreakingAfricanman January 14, 2014
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It’s when a woman ghosts you after first time sex. This is appreciated amongst most men statistically
Kabir: Did you get lucky with Jessica?
Imran: Yes. I’m also lucky that she pulled a vanishing pussy syndrome. I messaged her & nothing
Arjun: Sweet. I always have to do the george costanza break up routine. Yuk!
by rtalati January 25, 2022
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When a woman thinks she is worth more than gold based on her looks or the mere fact that she has a vagina and therefore men should worship her and or spend money on her.
1. "That KylieJordan must have golden pussy syndrome to think men will pay to be around her!"

2. "So this bitch at the bar TOLD me to buy her a drink, me thinks she's got a bad case of golden pussy syndrome."
by DoobiwUs September 27, 2010
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This serious mental affliction occurs when a female is under the false impression that her vagina ALONE has powers that surpass all other women on earth in the ability to keep a man. Also known as PPS
Most groupies & gold diggers suffer from platinum pussy syndrome, till those divorce papers roll through
by CBeezy74 January 2, 2016
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A guy that stays with a demanding, high maintaince/ low reward female, who walks all over him, ridicules him and removes his of all self esteem because she allows him to fuck her frequently. This often requires an intervention by family or friends in order to get him extracated from the relationship. May be abreviated TPS Symptoms : not talking with long time friends because she doesn't like them, telling him he needs to change( any habit that she finds she doesn't like), tearing him down verbally, to the point of depression, doing everything she wants and rarely does what he wants to do, needing to know where he is at all times, only lets him talk with with others that she deems ok and gives permission to talk, constantly is apologizing to her for some minor infraction, begs her to forgive him because she says that he is the root of all her dissatisfactions and problems in life, expects him to read her mind to meet all her needs and wants.
1-Did you see Myles? He looks terrible since shortly after he started seeing Emily and she started running his life. He has all the symptoms of Toxic Pussy Syndrome. 2-Hey, all the guys are taking Myles out to party tonight to help him recover from his TPS.

3- I can't believe that I got infected with Toxic Pussy Syndrome again. I thought I was immune to it after getting last t year from Emily .
by swamp stud- go gators October 26, 2009
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The theory of a Boltzmann brain is the chance of a brain spontaneously forming into existence, on the other hand Boltzmann pussy is the chances of someone having intercourse being nearly impossible.
“You have Boltzmann pussy syndrome my guy
by Pilk_man March 12, 2022
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Massive Pussy Syndrome or MPS.
This is better known as pussyitis.

A disease that targets the male species and causes them to be more like the female of the species.

Symptoms
-no longer enjoying the taste of beer.
-no longer liking sports.
-agreeing with your wife.
-listening to your wife.
-choosing to be with your wife instead of drinking beer with the guys/team after the game.
-unquenchable urge to shave your box 24/7.

Cure
-a night out with guys involving borderline alcohol poisoning and a strip club. Patient must be left on his door step and his doorbell rung for his wife to find.

Cure only works in some cases and may take several doses before a full cure can be obtained.
Teammate 1 - "Where did Mike go?"

Teammate 2 - "He said he no longer likes the taste of beer since he got the Massive Pussy Syndrome. Then he went home to shave his box!"

by CMAK in the shwa May 20, 2008
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