1 definition by SuperfreakingAfricanman
An affliction that effects men everywhere. Symptoms are similar to PMS, but much more extreme. They include nagging like a bitch, complaining about irrelevant events, and inability to continue being a productive human being. They also include weeping and moaning and other forms of whining.
"Is Mike coming to the bar with us?"
"Nahh. He came down with a case of pussy syndrome and is staying home to watch Glee."
"Nahh. He came down with a case of pussy syndrome and is staying home to watch Glee."
by SuperfreakingAfricanman January 14, 2014