"power the fuck up." during a long period of drinking beer, many partiers may become tired. it is up to someone to recognize this and tell everyone to "PTFU." this would include doing shots that include a sugary drink or simply becoming more active with an exciting drinking game.
ian: "dude, i'm about to pass out. too much beer."
ross: "screw that, man. PTFU!"
ian: "aw yeah, bro!"
by mombuttfacedad August 26, 2011

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