"Nature's callin" or "nature calls" is usually how nature's call is said in a sentence.

Guy #1: Dude, where you going so fast?

Guy #2: Nature calls!
by chocolate box July 22, 2006
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noun A term used to define, in a G-Rated dialect, the urge to take a massive dump.
1. Jimmy: You don't look so good. What's the rush?
Timmy: I have to answer nature's call!

2. Kimmy: Hey, what's up?
Bimmy: One moment, nature calls.
by cool guy with cool shoes June 6, 2015
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When someone says - nature calls - they mean they have to go to the bathroom - lool - WC -toilet.
during a conversation

john : have you heard about the new ipad

steve: nature calls brb dude

john : lol take your time
by dodopotter October 18, 2013
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A term in which during a road trip in the middle of nowhere when a person has to go & there is no rest areas nor travel centers around for miles.
Mom: Stop the car! Little Timmy has to go!!

Uncle Ray: Well looks like we got to make a Roadside nature call pitstop since there is not anything around for miles!
by BruinKiller3469 June 8, 2009
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when you have to take a crap or pee really bad
Hold on, mother nature is calling.
by fothermucker33 February 3, 2011
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