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1.
Means Heroin and is also a famous song by Guns N Roses on their debut album "Appetite for Destruction". When they are saying "Dancing with Mr. Brownstone" it means they are "Shootin Heroin"
"We Been Dancin' with Mr. Brownstone
He's been knockin he won't leave me alone"
by StraightUpWestSide June 17, 2005
 
2.
Heroine and/or shooting heroine.
Slip your arm in a bindle and fill your syringe with Mr. Brownstone.
by C. Filipe Medeiros May 20, 2005