This phenomena occurs frequently with Windows users, where when double-clicking on a file in which to open, the click is not fast enough, causing the file to be highlighted rather than opened. This usually causes the user to have to resort to using the “Enter” key instead.

This occurrence can cause low self-esteem particularly in older people as it draws into question the performance of their motor skills, leading to thoughts that maybe they are showing signs of early stages of Alzheimer’s or other neurological disorders (which is usually not the case).
“I saw a neurologist today on account of my increasing number of ‘double-click misfires’. He assured me that nothing was wrong with my motor skills and suggested I simply adjust my mouse settings.”
by Johntoo August 22, 2009
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When an individual who has been exposed to an elongated period of seemingly subarctic temperatures gets in their car and, lost in their innermost desire to reach homeostasis, blasts the heat in the car to notch 4 (two notches from maximum). After a period of 4-6 minutes depending on the quality of the cars heating system, the person begins sweating profusely and could possibly undergo severe hallucinations. This unfortunate heating mistake is commonly referred to as a notch 4 misfire, not to be mistaken with a notch 2 assassin. (see also)
Fred: It's freezing!! I neeeeed heat!!!
(period of 4-6 minutes depending on your heating system)
Fred: Sweet mother of god it's hotter than hells ballsack in here! This was a notch 4 misfire if I ever saw one!
by notch4 October 29, 2011
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being too lazy to nut into a sock, tissue or even your hand, resulting in you nailing yourself in the face.
Never spray 'n pray, its not worth a critical misfire
by fagmaster69696969699696420 March 11, 2021
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When you’re pegging your girl from behind and she pisses and shits on you at the same time.
My girl had to go to the bathroom but I made her fuck anyways which resulted in an unfortunate Texas double barrel misfire
by Plain ol dumb April 13, 2022
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When you’re pegging your girl from behind and she pisses and shits on you at the same time.
My girl had to go to the bathroom but we fucked anyways which resulted in an unfortunate Texas double barrel misfire.
by Plain ol dumb April 13, 2022
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The act of aiming your dick at your girlfriend's cat just as you cum.
Person 1: "Did you see how Jeff pulled a meowy misfire yesterday??"
Person 2: "Yeah, I had to clean it up myself!"
by AssRipper5000 June 6, 2020
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