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The phrase that you use in a time of utter disbelief. Overwhelmed with an unability to "Make it up." Usually it seems like if you actually tried to make up a story or something creative, it would be more believable than the actual events that have occured.
Chris: Jesus Christ dude they just bombed the Twin Towers.

Adam: You can't make it up bro.
by youngdog September 07, 2012