Top Definition
Used to avoid actually coming out and calling the person a ho to their face/behind their back. Use responsibly.
Danika: Look at that girl sitting next to Hot Guy.
Lisa: Don't worry she is a Hydrogen Monoxide, he won't be interested.

"I feel like such a Hydrogen Monoxide, I burned 400 calories five times this weekend!!"

Marissa: You're such a hydrogen monoxide
Blonde girl: Like, what?
Marissa: Exactly.
Blonde girl: Well...Thanks!
by Danisa Lisika April 11, 2008

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