1. A word used to call your friend. First started in the 1990's, most commonly featured in the Fresh Prince of Bel-Air.

2. The guy who goes out of their way to be a douchebag. Most commonly found in the city of Guelph.

by pr0n0 August 13, 2006
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That one legit drug dealer u can find anywhere with a low profile. He/she doesn't give any fucks about getting caught and they will keep going
Aye do you see that girl over their

She got caught 3 times selling drugs and she still does it

She is totally a Holmes
by Carlosmendez April 3, 2018
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1. in referance to Sherlock holmes
calling someone a smart ass or an insult in calling someone whehn they are trying to act smart and point out the ovious
2. sexy old neighbor somewhat a wigger but nonetheless a good guy with a hot superman ring.
3. slang What you could call a friend, a stranger, or use a mocking someone for being differnet
4. sarcastic comment calling someone a smart ass
-thanks holmes (sarcastic)
-ya shut up wattson

-sup holmes?
-nm wat bout u?
-nuffin g2g tho c ya home slice
-pc easy
by sexybitch March 2, 2005
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A derogatory term meaning a big dick. After John Holmes the porn star. Usually confused with "homes" short for home boy or homey.
Used as an inside joke with a person who is a pest. "What's up Holmes?" Instead of "What's up you big dick?"
by Ghost of Holmes August 1, 2005
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The King of Kings, God of Gods. An extremely ripped and buffed person. A natural born leader, a warrior, true fighter and most of all - The One.
Men look up to holme.
People wanna be holme.
People train their entire life to become LIKE holme.
by mortenh February 28, 2012
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1) A very cool person
2) A nice person
3) A second term of the word "Homie"
"My mom is the holmes!"
"Dude. You are totally the holmes!"
"The bitch is the holmes!"
by McLoViN BiTcH July 11, 2008
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The potato spelling of "homes (See: homeslice, homeboy, Better Homes & Gardens)

Person 1: Whassup, holmes?
Person 2: You're an idiot.
Person 1: Sup, holmes. What's good?
Person 2: Not your spelling, you raging idiot man-child
by <JebTex> January 25, 2019
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