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1.
The remnants of masturbation. Generally includes semen, lotion, and other fun things.
"Geez, why won't this hand cheese come off?"
by onbusmis February 22, 2009
 
2.
When a guy jacks off and he doesnt clean himself up afterwards so his cum turns into hand cheese.
Don't touch that guy or else you might get his hand-cheese on you!
by theblacksheep February 22, 2009