A combination of the names George and Izzie.
Comes from the television show Grey's Anatomy. Fans of the show use it to refer to the relationship between George O'Malley and Isobel "Izzie" Stevens.
Oh my Gawd, Gizzie is so retarded. He should have just stayed with Callie.
by eulalie27 May 13, 2008
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(N.) A stupid, assclown who likes Anti-rap like Ja Rule and Too Short. Suck a d*** you stupid skank!
This dumb Gizzie Mcguire bitch likes DJ Too Dope and Ja Rule. Let's throw some 99 cent "Irv Gotti Presents.." albums at her bitch ass!
by G-Union May 12, 2003
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to be very exciting and hyped up.
'The Bomb Digz were gizzy last night.'
'Im too gizzy today.'
by reginesogizzy July 21, 2015
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The best Counter-Strike player ever:

GiZzY
OMFG! GiZzY is the best non-hacking Counter-Strike player EVER!11!!!ONE!11!
by Jason(/-_^_-\)X August 17, 2005
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Another way to say you got sum real gas pack !! Sum dope ass weed every time
“This Sunset Sherbet gets me hella blasted !! This prolly my favorite strain rn!”

“Yump I really like that tree it’s sum true gizzy !! I make sure I scoop gizzy pack every time.. I don’t do the Reggie
by Bigdaddyjade September 1, 2020
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Slang For >Mustela putorius furo< The Domestic Ferret
You better catch Gizzi Before it escapes from the fridge with the treats.
by The Gizzi Catcher February 2, 2010
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