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1 definition by eulalie27

A combination of the names George and Izzie.
Comes from the television show Grey's Anatomy. Fans of the show use it to refer to the relationship between George O'Malley and Isobel "Izzie" Stevens.
Oh my Gawd, Gizzie is so retarded. He should have just stayed with Callie.
by eulalie27 May 13, 2008
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