The condition of getting a sore/blistered thumb from playing video games for an extended amount of time.
"I played God of War II last night for five hours and i hadd to quit because i got gamer's thumb."
by zits24 March 30, 2007
The condition where a person's thumb becomes permanently disfigured due to playing video games, often results in a bump or oddly flat spot on the pads of both thumbs
Hey, my thumb has the weird flat spot on it. Oh, that's probably Gamer's Thumb
by PriorDread December 13, 2013
where someone who has played videogames too much resulting in their thumb, when bent, has all their thumb padding near the joint where the analog stick would not be.
gamer: Hey dude, look at my thumb its like gone all retarded
friend: thats normal for a l33t gamer. Its called gamers thumb
gamer: really? will it be normal agian?
friend: no ur not a l33t gamer, and yeah ur stuck with it like that
by 2Ninja4U August 27, 2009
An extrememe condition where a gamer rectally penatrates ones self using their thumb due to sheer loneliness or boredom.

There is little information about cures to this condition.
Some reports state that interaction with females can reduce symptons.

/or/

The ache's and pains felt around the thumb and hand after long intense sessions on console based shoot 'em ups

ohnoro loves his gamers thumb

ohnoro hides his condition but everyone knows its gamers thumb

ohnoro: "Oh sweet jesus, its stuck"
afinemess: "woah, what're you doing?"
ohnoro: "gamers thumb =("
by shiftlaxdaddy June 04, 2008
What happens when viral web sensation (and time traveling Mongolian warlord) hngryGenghis cuts off of his opponent's after he has beat them at a coin-op, console or PC video game.
I can't hitchhike anymore because I lost two times in a row to hngryGenghis and now I have a severe case of Gamer's Thumb.
by hngryGenghis September 20, 2010

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