Pain associates in the right thumb of a gamer, This is caused by moving the thumb off one button to the next with out rolling the thumb. This is associated with most systems that have buttons in a diagonal form but the Gameboy's format is at a 40 degree angle and not a 45 degree angle. Being that the D-Pad buttons on most controllers have not changed since the NES and they are close enough so you can roll the thumb causing less stress then having to take the button on and off a button in order to do actions.
Gary: Man I found my old Gameboy in my closet!
Lance: That is great did you find any games?
Gary: Yes my old copy of pokemon gold, and link's awaking DX.

Lance: Cool how long did you play?
Gary: not long after about three gyms I got Gameboy thumb
by The true Gameboy God February 3, 2012
Get the Gameboy thumb mug.
Herald to the renaissance of video games. Scourge of the 3D world. Competitor of home consoles. Object of envy to Sony and N-Gage fanboys.
Teh GAYBOY LAME-ASS is teh sux0rs cuz it has kiddy game lyk pOkemon and sonic. Evry1 noes dat grafix and overdone stories is what makes teh good game.
by Solieyu December 30, 2004
Get the Gameboy Advance mug.
The Gameboy Advance SP used by the Pope, for when he's not blessing people. Has been known to cause small miracles, such as turning water into wine and curing diseases. Also known as a Poboy or Popeboy.
"Yo homey, can I use the Poboy?"

The Pope: "Only if the Lord will let you, gangsta
by Monkeyman November 23, 2004
Get the The Pope's Gameboy mug.
a very classic console with color so i can be a jerk to the color designers yay
guy 1: wanna play gameboy color
guy 2:no its not multiplayer
guy 1;oh yeah
by YOUFART December 14, 2021
Get the gameboy color mug.
The Gameboy Rockstar is the most unrated rapper/singer of all times😭😭.
The Gameboy Rockstar
by The Gameboy Rockstar March 11, 2021
Get the The Gameboy Rockstar mug.
a really tiny version of the gameboy advance, Thus another way for nintendo to make money by releasing somthing that can do the same as the gameboy advance and gameboy SP. But people will still go out and buy it anyway.
jim: cool the gameboy micro! i gotta get it even tho i do own both Gameboy advance and Gamboy advance SP...
by Aiden Lee November 7, 2005
Get the gameboy micro mug.
A device for the Gameboy which specializes in creepy error faces that looks like pedophiles waiting to snatch you. One reason why im afraid to hook out my dog during the night
Did you hear about the ducktape bandit? Thats scary
Forget about that mofo! Im afraid of my gameboy camera.
by Bryciekai January 24, 2014
Get the gameboy camera mug.