In roleplaying, a save one rolls to resist certain effects, such as poison, sleep, fatigue, etc. Based on the Constitution score.
"Make a fortitude save."

"I rolled a one."

"You die of poisoning."
by fanficbug May 5, 2006
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Balls, as in courage or bravery. See also chutzpah.
He doesn't have the testicular fortitude to challenge me to a fight!
by JohnQPublic March 25, 2007
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Courage; a term coined by WWE wrestler Mankind, from the term "balls" commonly used everywhere.
You don't have to testicular fortitude to hit me with that steel chair!
by Julio Christ June 11, 2006
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"guts" displayed by the fairer sex, or women collectively.
She displayed a lot of ovariological fortitude in the squared circle.
by weave March 17, 2003
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