To be defeated or beaten on many levels in many facets of life including but not limited to sports, school, and fisticuffs.
The inability to succeed at anything despite enormous effort.
Jane: Last week Bobby spent 24/7 studying for his Biology final and he still failed.
Alex: I know. Even the kid with a 65 IQ topped his score. He has a major case of Foot-In-Ass Disease.
by OneLostChapter February 15, 2008
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A horrible smell that comes from a wall locker as a result of sweat-soaked clothes piled upon each other over a long period of time. Usually occurs with college students stockpiling their dirty laundry.
Holy shit Travis, this room smells like foot and ass disease!! When was the last time you washed your nasty ass clothes?
by UMC February 1, 2008
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