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Fyfo is an acroynm for Fuck ya face off. Commonly used in utter disapproval, hate rage, or just to be a dick. Replaces the old saying, "Wipe that smirk off your face."
Dude1: You think that's funny? Wipe that smirk off your face!!!

Guy2: Fyfo fuck ya face off first.
FYFO by Nate Blaze July 1, 2011
Related Words

fe fy fo-fugly 

A term used to describe a very very large ugly person.
Dude, your WNBA girl friend is fe fy fo-fugly
fe fy fo-fugly by big-c June 11, 2006

fi fy fo fum 

Fi fy fo fum I love to swallow cum
fi fy fo fum by Imthehamman August 5, 2023