look up any word, like cunt:
 
1.
To be High and out of your mind. (Turnt up)
This herb gotta nigga EFFE.
by Jrock3000 November 24, 2013
 
2.
Italian slang for a very passive homosexual.
italiano per ommosessuale passivo
At gay therapy, the effe in the relationship complained why he has to take the cock everytime.

alla terapia ommosessuale, il effe dal rapporto ha reclamato perche' il cazzo ha prenderlo tutti tempi