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1.
Duu
Describing the feeling of being pouty or upset. Stems from the sound one makes when pouting one's lips.
Can be used as an adjective or verb.
I failed my test today; it makes me so duu.

Duu! I can't watch the movie with you guys tonight!
by chenxjen July 27, 2010
 
2.
Duu
Ghetto meaning of the word "dude"
Man duu im finna go do dat
by Lindsey4real October 18, 2008