Chem-chal Share definition Flag A negative emotional state, due to an imbalance of chemicals in your brain (dopamine etc). Domus: " Why is Rachel acting strange tonight? " Thomas: " Because she's Chem-chal. " Chem-chal by 401Sparky July 20, 2012 0 0 Get merch Get the Chem-chal mug. Buy Now — $32.95 See more merch