A chemical, drug-induced party sweat left in & on your clothing. Often after a party, but sometimes when you're at home watching internet videos at 5am.
After that New Years party, my blazer had a wicked Charlie Sheen.
by John Hollick December 31, 2014

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a drug that will make your face melt off and your children weep over your exploded body.
I'm on a drug. It's called Charlie Sheen.
by bigdaddylemon March 17, 2011

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Simply Winning
Kobe Bryant did a Charlie Sheen for hitting that game winner vs the Suns.

Kobe Bryant also did a Charlie Sheen for getting away with rape. "I didn't do it." Wife, "I know you did." Kobe "Did I?" pulls out 8 carat diamond ring. Wife. *shakes head* unzips his pants.
by thisdude4545 March 11, 2011

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The only person who is able to beat up Chuck Norris. Charlie Sheen's immortal body filled with tiger blood, and fire breathing fists is the only counter to Chuck Norris' god-like abilities.
Chuck Norris : prepare to be roundhoused to the next dimension.

Charlie Sheen : I am filled with tiger blood, and win.. imagine what I could do with my fire breathing fists.
by oredith March 09, 2011

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A type of drug.
Reporter - Charlie, what type of drugs have you taken?

Charlie - The only drug I'm on is Charlie Sheen.
by EJ Isla March 05, 2011

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Your very own psychotropic drug and/or alcoholic and/or drug mixture
hey dude, try this shrooms and tequila it's my charlie sheen, gets me f'ed up and superpowered with fiery fists
by nottinmatterz February 28, 2011

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a manwhore who is always drunk or high and has no respect for women
hes just like charlie sheen, a whore
by Clair H. June 11, 2015

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