Top Definition
Acronym for Center of the Universe Syndrome.
On a crowded sidewalk, she just stopped dead in her tracks, with no thought for anyone around or behind her, to answer her cell phone. What a COTUS!

He spent 15 minutes at the drive thru window, just chatting away, not the least bit concerned with those of us who only have an hour for lunch. He's suffering from a serious COTUS.
by tribblemaker January 28, 2013
an acronym for child of the universe.
don't fuck with these people unless you like to loose.
"who is that amazing human?"

"oh that's cotu, he/she is a wicked amazing sexy genius."
by zombse sutures August 22, 2008

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