the come down after a night or weekend of drinking/partying. The blue feeling you get because you had so much fun during the weekend and now it’s over and you’re just lonely afterward. Too much stimulation and then you just feel womp womp. Usually felt on a Monday or Sunday night.
"I have a bad case of the booze blues."

Friend 1: At work right now and feeling crummy and sad
Friend 2: Dude, it's just the booze blues talking.
by Trillbo Baggins February 11, 2015
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The depressed state one sometimes experiences after drinking heavily for two or more days. May or may not be accompanied by a hangover; can cause the sufferer to become overly emotional and/or cry for little or no apparent reason.
Dude...are you crying along to a Taylor Swift song?

Sorry, I have major booze blues after partying in Vegas all week.
by Meredith G. October 21, 2011
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The sorrow one occasionally feels when drunk. Usually occurs when one drinks when he/she is in a bad mood. The affected person will often be saddened by anything and/or everything wrong in that person's life, no matter how important or trivial (most often trivial). Often accompanied (but not remedied) by more drinking.
Bob- Fuckin spilled my drink again...*sniff*...'can't do anything right. *eyes watering*
Steve- hey man, it's cool; I'll get you another one. It was just Popov anyway.
Tim- Is Bob alright?
Steve- Eh, you know, he's just got the Booze Blues, is all.

-Toilette's backed up again...*sniff*...WHY ME?! WHY NOW?!
by The Bourbonator April 25, 2011
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Booze Blues defines the depressive state after drinking alcohol and thinking about things too much.
Bob was thinking about his messed up relationship last night at the pub, he had a major case of the booze blues
by matty spatty March 15, 2008
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The nagging and persistent melancholy that follows a night and/or day of binge-drinking, especially if you have done something regrettable during that time. This is usually coupled with a hangover.
"I was laying in bed all day with a bad case of 'post-booze blues', after unsuccessfully trying to hook up with my boss last night at the Christmas party"
by Ned Shaver December 11, 2009
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