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Pronounced "four, five, six", rather than "four-hundred fifty-six".

An alien race from the Whovian universe that came to earth in 1965, asking for 12 children in return for the vaccine to an Earth-born disease that was about to mutate, killing thousands. They were named the 456 after the radio waves they first used to communicate with the United Kingdom's government.

The 456 are large, with three heads, large mandibles, and trunk-like in body. Each has a large bulge at the end of it's body, revealed to be a holding area for children. They live in a very toxic environment.

The 456 returned to Earth in 2009, demanding 10% of the world's children, in return for the safety of the entire world. They announced this return through children, as if using them like radios: "We. We are. We are coming."

The 456 later revealed they wanted the children for personal pleasure, stating the children "felt no pain", and that the prepubescent hormones were like a euphoric drug, connected to their bodies through veins.

The 456 were defeated by Torchwood soon after arriving, but not without losses (Ianto Jones and Steven RIP). They were driven away from Earth, the radio waves they had used to communicate being turn against them.

"Children of Earth" is the mass episode title for the five days the 456 were present in 2009.
Voice: "You call us 456"
John Frobisher: "That is correct."
Voice: "Then that is our name."
456 by Wren Felidae November 8, 2009
How to agree with the expression 123. 456 suggests strong consensus, if not unanimity.
"The latest In Flames album sucks dick through a straw."
"123" ("I agree.")
"456" ("Me too.")
456 by 1338 h4x0r April 1, 2008
Having faith in our happily ever after ❤️ Realizing we are here and i had no control in it!! Wanting to speed up the process because there is nothing i have wanted more... but impatiently understanding i can’t.... you and fate appear to have this🙏🏻

I see you and I want to jump.. wrapping my legs around you while hugging you!!! And never letting go!! But instead I just watch you walk by and smile...knowing someday❤️❤️❤️
456; someday... is what I live for... to be with you!!! I love you!!!! And want nothing more than to be one with you!!! 17
I am so in love with you!!!! I will wait an eternity for you!!!
456 by 4u my love will never stop September 13, 2022
From the phonetic sound produced when saying "for f*cks sake", or ffs
456 by gay camping n00b November 4, 2003
Just a fucking number that's close to 420
Person 1: what's the date?
Person 2: it's the 456 lol
456 by OnceAManNowANarwal September 15, 2019
456 people will risk their life for cash
456 by Hackerslayer/Toxicslayer November 24, 2021