Top Definition
Pronounced "four, five, six", rather than "four-hundred fifty-six".

An alien race from the Whovian universe that came to earth in 1965, asking for 12 children in return for the vaccine to an Earth-born disease that was about to mutate, killing thousands. They were named the 456 after the radio waves they first used to communicate with the United Kingdom's government.

The 456 are large, with three heads, large mandibles, and trunk-like in body. Each has a large bulge at the end of it's body, revealed to be a holding area for children. They live in a very toxic environment.

The 456 returned to Earth in 2009, demanding 10% of the world's children, in return for the safety of the entire world. They announced this return through children, as if using them like radios: "We. We are. We are coming."

The 456 later revealed they wanted the children for personal pleasure, stating the children "felt no pain", and that the prepubescent hormones were like a euphoric drug, connected to their bodies through veins.

The 456 were defeated by Torchwood soon after arriving, but not without losses (Ianto Jones and Steven RIP). They were driven away from Earth, the radio waves they had used to communicate being turn against them.

"Children of Earth" is the mass episode title for the five days the 456 were present in 2009.
Voice: "You call us 456"
John Frobisher: "That is correct."
Voice: "Then that is our name."
by Wren Felidae November 08, 2009
automatic win in ths dice game, ceelo
damn! i just lost 10 dollars because that bitch won with a 456
by bigmomma March 19, 2007
it stands for the 40's,50's, and the 60's which are street numbers that make up north oakland.
If u from da norph then u gottah say u from da 4-5-6
by J.DuB May 27, 2005
a new short phrase to replace " for fuck sakes.. " when said quick enuf 4-5-6 sounds similar..

made up by way cool older sister when we were kids and is stil in use today ... was an attempt to be smarter then my parents at swearing..
OH!!! 4-5-6 ( OH! for fucks sake!"
by Lori October 22, 2004
From the phonetic sound produced when saying "for f*cks sake", or ffs
"456 stop spawn killing"
by gay camping n00b November 04, 2003
How to agree with the expression 123. 456 suggests strong consensus, if not unanimity.
"The latest In Flames album sucks dick through a straw."
"123" ("I agree.")
"456" ("Me too.")
by 1338 h4x0r April 01, 2008
From an automatic win when rolling dice in ceelo, used as an adjective to describe any best-case scenario.
"I found a winning lottery ticket in my new office after my promotion when I was banging the infertile supermodel secretary they imported for me. Today was 4-5-6."
by InstantRamen February 09, 2010
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