A chain reaction intentionally rigged to accomplish a task; inspired by Rube Goldberg (1883-1970)
My coffee maker doesn't have a timer, so I use the Goldberg Effect starting with the alarm clock ringing in my room, then BING! BOOM! BAM! The last rig flips the switch on my coffee maker.
by J t 500 September 25, 2007
Get the Goldberg Effect mug.
is when a girl or man keeps getting there butt slapped till it gets a red color, usually during sex.
Dude, while we were doing it i kept slapping her ass so much i think i gave her a Woopie Goldberg.
by zerobeat121 January 19, 2012
Get the Woopie Goldberg mug.
When a nice guy looks like he has done some shady and dark shit. He starts by being the nicest guy ever, treating everyone around him with love and respect, just an all around good guy. Until everyone including your friends and loved ones realize he isn’t who he says he Is except for the woman who’s in love.
Friend girl 1: ooo that guy over by the table looks cute and nice..
Friend girl 2: but he’s giving off some Joe Goldberg Syndrome vibes..
by WhiteLightning May 24, 2020
Get the Joe Goldberg Syndrome mug.
n. The situation whereby a medical or medical/psychiatric condition causes a "domino effect" of other dangerous symptoms and conditions ensuing.

Named after the Rube Goldberg "contraption" machine, any machine that uses a chain reaction of events to achieve a final, trivial goal (in this particular case, possibly death).
After my brother had that bout with strep, it apparently got to his stomach and paralyzed it, giving him a nasty case of acid reflux, which in turn began to launch acid clear up into his throat and mouth, not only severely damaging his teeth... he's also he's worried he's going to get cancer one day from all that acid where it's not supposed to be. And to say nothing about all the dental surgeries he's gonna need... talk about a case of Rube Goldberg Syndrome!

(No really, it has happened.)
by Andy Khay January 23, 2009
Get the Rube Goldberg Syndrome mug.
Dr. Brandy Goldberg is one of the leading Pharmacologists of our generation, and inspiration to the younger generation on reddit.
My name is Dr. Brandy Goldberg. Purdue Pharma, CT. I have a PhD in Pharmacology. Google me if you want to read my autobiography.
by The Dictionary Beast April 3, 2021
Get the Dr. Brandy Goldberg mug.
Drunkenly setting a series of events in motion that ends in tragedy.
"How did the fire start?"
"Well, Mark was wasted and in reaching for his cell phone knocked over a glass, that fell on a power strip, that set the couch on fire"
"I see, classic Rube Goldberg Alcoholism"
by Bourbonsauce January 21, 2010
Get the Rube Goldberg Alcoholism mug.
Basically, a 'machine' that uses many ordinary items, and positions them in a way so that when activated, sometimes by 'knocking down the first domino' so to speak, it leads to a series of events that are all activated by the previous events.
They are most always elaborate, with many things going on at one time.
They are hard to build, and sometimes take over 4 months and a millions hours to build, but the results are spectacular.
Child 1: Hey, let's play Mouse Trap!
Child 2: I heard that's something called a Rube Goldberg Machine!

Teen 1: Have you seen Ok Go's new video, 'This Too Shall Pass'? It's totally a Rube Goldberg Machine!
by loveisjujujubaby March 14, 2010
Get the Rube Goldberg Machine mug.