An exclamatory phrase used in response to a friend's minor medical calamity.
Margaux: Don't eat the spinach! There's a salmonella recall!
Michelle: (chomping away)...huh?
Margaux: Yikes...

Raj: I got a mosquito bite on the hump of my nose! It looked like it came straight out of an antisemitic drawing!
Jenny: Yikes!
by Kung Fu Sammy July 5, 2011
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An informal exclamation used when someone says something so incomprehensible or ridiculous that it's not worth correcting or trying to debate.
> You know, Crooked Hillary sold child slaves at that pizza shop!!
> yikes.
by ntp479 March 14, 2018
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A reaction to when something terrible, awkward, shady, or odd happens.
"I saw Sarah leave the back room of the party last night with Freddy but today she's holding hands and kissing Jason."

"...Yikes."
by cheysshi April 11, 2016
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The past tense of saying yikes to something
by stubbornmirror March 8, 2022
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A response for when someone tells you bad news.
Leander: Bro I got raped and now I have a std.
Noah: Yikes Dude.
by YikesDude May 30, 2023
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twitch.tv/burpboy is sponsered by yike.
by iamshaw June 25, 2018
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Modern slang for breaking-up with someone. Commonly misunderstood for "yikes" which is used to imply something is negative.
"if what I think on that subject is actually a problem for you... Yike."
by Ciara Genni November 18, 2022
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