your on the phone and your man ask you do you want me to buy you something from the store and you i guess so.
by OSHI March 24, 2005
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Sort of like "you do you," but with a strong implication that you're talking out of your ass. Basically "you're an idiot and what you're saying is stupid, if you want to keep going I guess I won't stop you."
Bob: "The world is run by lizard people."

Sue: "There's no such thing as lizard people, but go off, I guess."
by Mai Ainsel July 1, 2020
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What you say when someone tells you something he thinks is hilarious but really isn't. You say this to avoid hurting your friend's feelings in breaking it to him that his joke sucks.
Dudeman 1: "Oh man, I was playing horseshoes in Red Dead Redemption and I got a really close throw and John was all like, 'Did you see that!' It was so funny dude!"

Dudeman 2: "I guess you had to be there."

Dudeman 1: :(
by Izzy del Bosque June 9, 2010
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A half-hearted yes, or simply agreeing with someone for the sake of responding.
Victor: If you say "I mean I guess," one more time, I swear I'll stop talking to you.
Kaylee: I mean I guess.
by Ultimate Salty Kitty Cunt March 28, 2016
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1)When you are trying to do something in a game. Ususally a bad outcome resulting in being pancaked or hit and run in UT3 or being impact hammered while trying to shock combo.

2)When someone screws you over.
Oh, i just got ran over by the scavanger. I guess that's cool.

Paul: You went to taco bell and didnt tell me? I guess that's cool.
John: I didnt know you were here!
by John Erwin June 20, 2008
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When someone is proven to be wrong/stupid/lying, but you'll entertain them anyway.
You know we didn't sleep together, but go off I guess.
by Scratch 'N Sniff Asshole March 4, 2021
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