he tweaked the radio dials, hoping to peak the signal into intelligibility
by Jake February 25, 2004
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To describe someone that is out of thier mind or making a mistake.
"Ohh did I say 6:00 o'clock? I ment 5:00, I'm tweaking!"
by Ashleysophia December 6, 2007
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High on meth/crank. See also "Smebbin".
I was tweaking so hard I couldn't see straight.
by KOW October 11, 2002
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1. Customise or modify (something) to suit a particular individual or task
2. Improve (a mechanism or system) by making fine adjustments to it

synonyms: adjustment, modification, alteration, change, adapt, customise
I am going to tweak the design a little more on photoshop
by eslupmaet June 16, 2014
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To injure slightly, to sustain a slight injury to (some part of the body), usually while playing a sport.
"The pitcher tweaked his groin on a grounder back to the mound."
by RB Jr. July 18, 2006
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To be Up and Fidgity From doing Crystal Meth.
When It's 4 AM U havent slept for days and Ur still wide away your TWEAKING
by Lisa April 9, 2004
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