Having extra chromosomes. Symptoms: acting retarded, telling jokes that don’t make sense and aren’t funny then trying to explain them, reselling, having sexual attraction to ones pet
by Immigrant_Kid March 30, 2020
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Down Sydrome is simply one of the most hilarious forms of mental defects around. If you can't laugh at Down Sydrome, you can't appreciate it.
That's the stupidest thing I ever heard, bitch must have down syndrome or something.
by Matthew D. Dillon April 18, 2008
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Beautiful. Yes, these people might have been born different, but they are beautiful. They will always fill your life with so much love and laughter and hope and joy. They are some of the most beautiful people you will meet.
Person 1: "Haha, yeah they look stupid."

Person 2: "Hey! He has down syndrome. Quit making fun of him. Theres nothing wrong with him."
by abuto_triangle January 14, 2018
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A violent attack to the head/ brain in effort to disable main functions of the human body.
"Look out, that black dude looks like he just Down Syndromed someone".
by James Hoy May 14, 2009
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A term for an addiction to the band System of a Down
Mike listens to System of a Down all day, he has down syndrome.
by m-dubya May 28, 2005
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Even god finds them funny.
Down's syndrome kid: "Help me, my eyes are r8 small but ma head's pure massive"
Guy watching: "Hahaha oh my god you should be put down."
by sdw298 May 5, 2008
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