Term originated by Lil Boosie. It is an abbreviation for "Bucked up and Fucked Up". When you are BUFU, you're drunk and or having fun.
by Lilboosieadvocate January 24, 2014
by Anonymous May 13, 2003
by radiomemory July 31, 2003
"...all the way out to bum-fuck Egypt."
by John (SC) January 18, 2005