A slang term for South Holland, a village in Cook County, Illinois, in Chicago's southland.
Where around Chicago do you live?
I'm from SoHo!
by littlebird February 16, 2007
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1) A woman who lives, works, or exists in the SoHo neighborhood of Manhattan. Typically wealthy, well-dressed, and not very bright.

2) A woman who will do anything to advance in the art world.
1) While in NYC, beware of SoHoes wearing silly hats from fc*uk.

2) I can't believe Sara sucked off that guy just so she'd get her own gallery. She's such a SoHoe!
by Jordan March 14, 2006
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a ridiculously good looking man. typically an asshole, and almost always a guido.
SOHO=SOHOt
heather:"oh my god check out that guy right there."
Brittany:"yeahhh hes such a Soho."
by brittsexy August 8, 2010
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a term for a guy or girl
towards a guy means (goodlooking but cocky/asswhole)
towards a girl means (whore/acting slutish)
did you see amy at the club last night she was totally acting like a soho.

wow i talked to kenny lastnight i like him but he's such a soho
by liyah foster April 8, 2011
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A store in a mall that sells fine jewelry.
When i was at Westroads Mall we went into soho.
by kristi March 2, 2005
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