What you call a fellow vato, basicaly means homeboy
whaddup ese?

f*ck you, ese!

ese! you owe me money, holmes
by Mexican-Desperado December 8, 2003
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ESE means the letter "S" which stands for SURENO or southsider. So that's why Mexicans that are surenos use it.
Yo homes most of you people are wrong. MEXICANS are the ones that use the word ESE. Some of us use it instead of saying the following:

foo,nigga,homes,leva,etc.
by Surena May 31, 2006
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The sexiest girl alive. Who is also smart and cute.Even when you play stupid games she kicks your ass.The bestest friend you can ever have. A non player girl who just knows what to do.
Did you see Ese she was so good at fuck last night.
by Carlden February 17, 2019
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Commonly mistaken to mean "homie," "buddy," or "gang coworker," this word is actually used as a password gateway into the telepathic community grid only known by Mexicans, Latinos, and anyone else who looks remotely like George Lopez. This telepathy internet has been accessed in secret by our people for a millennium, since the time of the Incas, Aztecs, and Bantu. Today we use this tool as a method of strictly important communication, usually to discuss common or new methods of pile-driving chika's, petty theft, or crossing borders. Anyone caught speaking this word intending to access our thought network will be located and drowned in beans, which we always have handy.
"Ese."
by Kenter January 31, 2009
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like nigga....for hispanics
yo ese, u best keep ur hands off my chica
by ruiz0012 January 18, 2005
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Friend, padre, homey. Used by Mexicans.
Hey, ese? What's happening homes?

Esses, are cool, they're the ones who took care of us.

I can't believe he did that to our dog, Ese
by Saints February 13, 2005
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Mostly used by Mexicans; Surenos or Mexican Gangsters; Ese basically means Homeboy or Friend.
Jose: "Hey Ese, look at that fyne hyna over there!"
Jesus: "Hold on Ese while I go holla at her."
by Manuella September 4, 2007
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