At the club, Patrick was about to get Bianca's phone number, when Al (ie the Closer) cock-blocked him by telling her Pat’s a nice guy… that lives at home… with his parents.
You and your lover are making your way to the bedroom, about to embark on a ride of sweet, passionate love making when you find your cat sleeping on the bed. This consequently denies you from sex since cats are too damn cute to be disturbed from their slumber.
1. when a guy who is interacting with a cute girl hoping to get ahead sexually is blocked from taking it farther by someone or something
2. either devine intervention, karma or poor luck preventing a guy from getting laid or succeeding sexual with a girl.
3. when a friend of either the guy or girl prevents the two from hooking up
I can't believe you just fucking cock-blocked me you prick, your like a cock-blocking dog that just pops up a the worst moment to fucking kill someones chance's of fucking scoring!