when you're feelin like a g and instead of saying 'omg' like boring people, you say 'omgizzle'. the second you say this you turn into a re-incarnated form of Tupac Shakurjust because you added the 'izzle' it makes that much of a difference.
O-M-G-IZZLES meaning omg that tickeld my tummy its often used when something seroious or funny happened usallay used by valley girls its feel good on your tounge : )
person 1: hey did you hear lydia got the lead in the school play