I mixture of the Scottish slang word 'mugged' meaning drunk, and 'muggle' the word for non-magic folk in Harry Potter. This is the ultimate Harry Potter fans's way of saying drunk.
'I was totally muggled on Saturday night! I drew glasses on myself in permanent marker and tried to fly on Katie's mop!'
It is said of the situation where a person has the bad luck to make contact with his testicles against an undefined surface or object, intentioned or not.
Given the nature of the word, it is more appropriate to design cases where the interaction is made with a moving object, for example, a ball.
Although it is extremely painful for the victim, it tends to be considerably funny to people who witness it.
Today in the baseball game the pitcher took a nutshot; the baseball hit him in the nuts.
Man, I just watched the funniest nutshot video ever.